As the U.S. Supreme Court prepares to take up the most significant abortion case in nearly 50 years, a dozen Republicans senators, including Utah Sen. Mike Lee, advocated for returning the issue to states.

The justices will hear arguments Wednesday over a Mississippi law that banned nearly all abortions after 15 weeks of pregnancy, allowing them only in medical emergencies or cases of severe fetal abnormality.

The case, Dobbs v. Jackson Women’s Health Organization, is a direct challenge to the 1973 landmark decision in Roe v. Wade. Mississippi also asked the court to reverse Planned Parenthood v. Casey, a 1992 ruling that upheld the constitutional right to abortion but allowed states to regulate the practice to protect the health of the mother and the life of the fetus.

Lee and the other GOP senators said in a news conference Tuesday that overturning the two cases would not outlaw abortion around the country, but allow for states to make their own laws regarding the practice.