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US President Joe Biden's Supreme Court pick is taking questions on her career and record from lawmakers on a key Senate panel over the next two days.
If the 22-member Judiciary Committee advances Ketanji Brown Jackson's nomination, she will be considered by a vote of the full 100-member Senate.
If confirmed, she would replace liberal Justice Stephen Breyer when he retires at the end of the court term in June.
So the political balance of the court would remain largely the same.
But it would be history-making because Ms Jackson would be the first black woman in the court's 233-year existence.
In her opening statement on Monday, the 51-year-old told the committee she would take her "duty to be independent very seriously".