Republicans have criticized her tweets, but Democrats say former President Donald J. Trump’s were much worse as they assail what they call a double standard.

Neera Tanden, you might have heard, has a Twitter problem.

Ms. Tanden, President Biden’s choice to run the Office of Management and Budget, has a yearslong trail of problematic tweets, many aimed at certain key senators who control the increasingly precarious fate of her nomination.

A procession of these senators — Joe Manchin III, Democrat of West Virginia, and the Republicans Susan Collins of Maine and Mitt Romney of Utah — have indicated that they are unlikely to support Ms. Tanden, in part because of the “divisive” and “overly partisan” nature of her tweets.

This has set the stage for the still-undecided Senator Lisa Murkowski, Republican of Alaska, who was asked on Capitol Hill on Wednesday for a real-time update on her own thinking.

As a visual aid, a Washington Post reporter, Seung Min Kim, showed Ms. Murkowski one tweet from 2017 in which Ms. Tanden had been critical of Ms. Murkowski after the senator praised Republican efforts to cut corporate taxes. “No offense, but this sounds like you’re high on your own supply,” Ms. Tanden wrote. “You know, we know, and everyone knows this is all just garbage. Just stop.”

“High on my own supply? That’s interesting,” Ms. Murkowski said, reading the tweet aloud for dramatic effect.

Interesting!