This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility: University of Illinois at Urbana-Champaign researchers have developed a CRISPR-based diagnostic tool capable of detecting bloodstream infections in minutes without the need for nucleic acid amplification.

This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility: Recently, scientists have been able to explore gene circuitry in individual cells using methods that suppress particular genes and measure the impact on the expression of other genes. These methods, however, fail to capture spatial information such as the effects from, or on, neighboring cells, which can provide important clues to a cell or gene's role in health and disease. Now, a technology developed in...

Ida Emilie Steinmark explores whether it can deliver on its promise Gene-editing medicines have had a rocky start. But there is cause for optimism But they may prove just as powerful Gene editing has put biological research on a new trajectory Science is becoming speedier, and more ambitious, in the age of CRISPR Former sceptics have come around to gene-edited crops. For the moment But there are possible pitfalls Will tinkering with human embryos ever be worth the risk? Gene editing can still change the world But it will take...

Deshawn “DJ” Chow waited a year to receive a treatment that could change his life. The 19-year-old was born with sickle cell disease, which makes his red blood cells crescent-shaped and sticky. The misshapen cells build up and block blood vessels, cutting off oxygen to parts of the body and causing episodes of excruciating pain. The condition affects about 100,000 people in the United States, most of them Black. The pain came more and more frequently for Chow in high school, landing him in the hospital often. He missed school,...

This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility: The identification of genes involved in diseases is one of the major challenges of biomedical research. Researchers at the University of Bonn and the University Hospital Bonn (UKB) have developed a method that makes their identification much easier and faster: they light up genome sequences in the cell nucleus.

This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility: Hybrid production in rapeseed faces several significant challenges, primarily due to the complexities and limitations of current male sterility systems. Traditional methods often involve intricate management processes and are highly sensitive to environmental conditions, resulting in unstable and inefficient hybrid seed production.

The treatment has a list price of £1.6 million and will be offered to people suffering from a genetic blood disorder often resulting from inter-cousin marriage. A treatment using the Crispr gene editing tool has become the first of its kind to be approved for NHS use, to treat patients with a rare, inherited blood disorder often found in those born of inter-cousin marriages. Hundreds of people living in England with a life-limiting blood disorder could be in line to receive the treatment, which has a list price of over...

This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility: A team from the Innovative Genomics Institute at the University of California, Berkeley (UCB) has produced an increase in gene expression in a food crop by changing its upstream regulatory DNA.

This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility: Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells. Hongjian Wang and colleagues at Wuhan University, China, present these findings in the open-access journal PLOS Biology.