The 3.5-magnitude tremor hit at 11:14 p.m. local time and was centered around 15 kilometers (9 miles) southeast of Ariel in the West Bank, the ministry says.
The IDF’s Home Front command says the earthquake warning system was not activated because the tremors did not pose a danger to residents.
Israel’s key area of vulnerability for quakes is along the Syrian African Rift, which runs through the Jordan Valley, down the eastern side of the country.