The Biden administration is pressing ahead with a concerted effort to strike a “grand bargain” in the Middle East that includes normalization of relations between Israel and Saudi Arabia, calculating that the U.S. could reap big rewards if it can overcome steep obstacles.

President Joe Biden’s aides have made this diplomatic push a foreign policy priority despite varying degrees of skepticism by experts on whether the timing, conditions and current regional leadership are right for a mega-deal that could reshape the geopolitics of the Middle East.

This marks a dramatic reversal for a president who had spent much of his term shying away from deeper diplomatic involvement in the region’s troubles, raising questions about why he has committed to such a challenging goal, what he stands to gain and whether he might end up paying too high a price.

A bid to broker relations between longtime foes Israel and Saudi Arabia is the centerpiece of complex negotiations that involve discussions of U.S. security guarantees and civilian nuclear help sought by Riyadh as well as Israeli concessions to the Palestinians, according to people familiar with matter.